MATK (9D7) Antibody
Product Details
- Cat. No.
- 252922
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
MATK (Megakaryocyte-associated tyrosine kinase) is a tyrosine protein kinase. MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of human MATK expressed in E. coli.
- Clone: 9D7
- Isotype: Mouse IgG1
- Gene: P42679
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Flow Cytometry (FC)
- Western Blotting (WB)