Product & ReviewsAntibodies
Matriptase Antibody
Product Details
- Cat. No.
- 251183
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Membrane-type serine protease 1 (matriptase) degrades the extracellular matrix. Matriptase is proposed to play a role in breast cancer invasion and metastasis. Matriptase exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Defects in matriptase are a cause of ichthyosis autosomal recessive with hypotrichosis (ARIH). ARIH is a skin disorder characterized by congenital ichthyosis associated with the presence of less than the normal amount of hair.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human matriptase.
- Isotype: Rabbit Ig
- Gene: Q9Y5Y6
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)