Product & ReviewsAntibodies
MDM4 (2D10) Antibody
Product Details
- Cat. No.
- 252801
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
MDM4 (Double minute 4 protein) is a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: "Purified recombinant fragment of human MDM4 expressed in E. coli. <br>"
- Clone: 2D10F4
- Isotype: Mouse IgG1
- Gene: O15151
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blotting (WB)