Product & ReviewsAntibodies
MEK1/2 (Ser218/222) Antibody
Product Details
- Cat. No.
- 252554
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Dual specificity mitogen-activated protein kinase kinase 1 (MEK1/2) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MEK1/2 activates ERK1 and ERK2 MAP kinases. Defects in MEK1/2 are a cause of cardiofaciocutaneous syndrome (CFC syndrome), also known as cardio-facio-cutaneous syndrome. CFC syndrome is characterized by distinctive facial appearance, heart defects and mental retardation.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Chicken, Dog (Canine), Human, Rat, Xenopus, Zebrafish
- Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser218/222 of human MEK1/2.
- Isotype: Rabbit Ig
- Modifications: Phosphospecific Antibody
- Gene: Q02750
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)