Product & ReviewsAntibodies
MEK5 (Ser311/Thr315) Antibody
Product Details
- Cat. No.
- 252557
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Dual specificity mitogen-activated protein kinase kinase 5 (MEK5) acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway plays a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis. Dual phosphorylation of Ser311 and Thr315 have been implicated in cell proliferation.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Chicken, Dog (Canine), Human, Monkey, Mouse, Rat, Xenopus, Zebrafish
- Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser311/Thr315 of rat MEK5.
- Isotype: Rabbit Ig
- Modifications: Phosphospecific Antibody
- Gene: Q62862
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)