Product & ReviewsAntibodies
Mili / PiwiL2 mouse antibody (mAb) (Clone 17.8), sample
Product Details
- Cat. No.
- 61144
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Mili / PiwiL2 is a member of the PIWI/AGO subfamily of RNA-binding proteins. Mili / PiwiL2 contains a Piwi and an AGO domain and binds a class of RNA called piwi-interacting RNA (piRNA), which are 24 to 30 nucleotides in length and are derived primarily derived from transposons and other repeated sequence elements. Mili / PiwiL2 is required for methylation and inactivation of retrotransposons. Mice deficient in Mili / PiwiL2 are sterile, as it is also required for spermatogenesis. It also positively regulates translation, and is required for germ line stem cell division and differentiation.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Mouse
- Clone: 17.8
- Isotype: IgG1
Handling
- Quantity: 10 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Immunofluorescence (IF)
- Immunoprecipitation (IP)
- Western Blotting (WB)