Product & ReviewsAntibodies
MKL1 Rabbit pAb
Product Details
- Cat. No.
- A8504
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - MKL1 antibody (A8504)
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Description
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
