Product & ReviewsAntibodies
MLH1 (4C9C) Antibody
Product Details
- Cat. No.
- 252800
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
MLH1 (DNA mismatch repair protein Mlh1) is a DNA mismatch repair protein. MLH1 is part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2, Turcot syndrome, Muir-Torre syndrome, including brain, colorectal, breast and endometrial tumors.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Monkey
- Antigen: "Purified recombinant fragment of MLH1 (aa381-483) expressed in E. coli. <br>"
- Clone: 4C9C7
- Isotype: Mouse IgG1
- Gene: P40692
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blotting (WB)