Product & ReviewsAntibodies
MLH1 (N-term) Antibody
Product Details
- Cat. No.
- 251332
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
DNA mismatch repair protein Mlh1 (MLH1) is involved in the repair of DNA mismatches. MLH1 is part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2, Turcot syndrome, Muir-Torre syndrome, including brain, colorectal, breast and endometrial tumors.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Dog (Canine), Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human MLH1.
- Isotype: Rabbit Ig
- Gene: P40692
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)