Product & ReviewsAntibodies
MLH1 Rabbit pAb
Product Details
- Cat. No.
- A0254
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - MLH1 antibody (A0254)
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Description
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse
