Product & ReviewsAntibodies
MMP-14 Antibody
Product Details
- Cat. No.
- 251938
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Matrix metalloproteinase-14 (MMP-14) specifically activates progelatinase A on the surface of tumor cells, thereby triggering metastasis. MMP-14 activates progelatinase A by cleavage of the propeptide at 37-Asn-|-Leu-38. Other bonds hydrolyzed include 35-Gly-|-Ile-36 in the propeptide of collagenase 3, and 341-Asn-|-Phe-342, 441-Asp-|-Leu-442 and 354-Gln-|-Thr-355 in the aggrecan interglobular domain.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MMP-14.
- Isotype: Rabbit Ig
- Gene: P50281
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)