MOUSE ANTI AMPK ALPHA 1/2
Product Details
- Cat. No.
- MCA2672GA
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
Human brain tumour lysate probed with Mouse anti AMPK alpha 1/2 (MCA2672GA)
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Description
Mouse anti AMPK Alpha 1/2 antibody, clone 84.1 recognises both the alpha 1 and the alpha 2 isoforms of AMP-activated protein kinase (AMPK). AMPK is a highly conserved heterotrimeric protein kinase found in all eukaryotes. The heterotrimeric complex exists as multiple isoforms and consists of a catalytic alpha subunit, which is stabilised by non-catalytic regulatory beta- and gamma- subunits. AMPK plays a vital role in maintaining cellular energy homeostasis and is activated by rising levels of AMP under conditions of hypoxia, ischemia, exercise, low glucose levels.AMPK may play an important role in the control of type 2 diabetes and metabolic syndromes. Recent studies suggest that AMPK functions as a suppressor of cell proliferation of both malignant and normal cells.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Drosophila melanogaster, Human, Mouse, Rat, Vertebrate
- Isotype: IgG2a
Handling
- Quantity: 0.1 mg
- Storage: +4ºC, -20ºC if preferred
- Buffer: Phosphate buffered saline, 0.09% Sodium Azide
Applications
- ELISA (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (Frozen Sections) (IHC (Fr))
- Immunoprecipitation (IP)
- Western Blotting (WB)
