MOUSE ANTI BOVINE CD45RO

Mouse anti Bovine CD45RO, clone IL-A116 recognises the bovine homologue of the human CD45RO cell surface antigen.CD45, also known as Leucocyte Common Antigen or LCA, occurs in a number of isoforms, clone IL-A116 is specific for the low molecular weight isoform termed CD45RO, the isoform associated with expression on memory T-cells. Bovine CD45RO is expressed by monocytes, granulocytes and subsets of thymocytes, CD4+ T cells and CD8+ T cells. Studies utilizing clone IL-A116 have demonstrated that the percentage of CD45RO+ CD8+ T cells increase from approximately 5% in neonatal calves to approximately 35% in adult cattle over the age of 5 years (Hogg et al. 2011). It has been demonstrated that mouse anti bovine CD45RO, clone IL-A116 immunoprecipitates a molecule of ~180 kDa (Bembridge et al. 1995) which is analogus to the molecular weight of human and mouse CD45RO.Mouse anti Bovine CD45RO, clone IL-A116 has been demonstrated to recognise the CD45RO cell surface antigen by flow cytometry in both European cattle, Bos taurus, and in Zebu, B.indicus (Bembridge et al. 1995).

• Clonality: Monoclonal
• Host: Mouse
• Reactivity: Bovine, Goat
• Isotype: IgG3

• Quantity: 0.1 mg
• Storage: +4ºC, -20ºC if preferred
• Buffer: Phosphate buffered saline, 0.09% Sodium Azide

• Flow Cytometry (FC)
• Immunoprecipitation (IP)