MOUSE ANTI EGF RECEPTOR (pTyr845)
Product Details
- Cat. No.
- VMA00748
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
Western Blot analysis of A431 untreated and pervanadate whole cell lysates
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Description
Mouse anti EGF receptor antibody recognizes the epidermal growth factor receptor, also known as proto-oncogene c-ErbB-1 or receptor tyrosine-protein kinase erbB-1, when phosphorylated at tyrosine 845. EGF R is a cell surface receptor for members of the epidermal growth factor family. EGF R plays a role in numerous cellular processes such as cell proliferation and apoptosis through the activation of downstream signaling pathways (Scaltriti and Baselga 2006). EGF R is phosphorylatedon tyrosine 845 by c-Src kinase (Biscardi et al. 1999). This modification modulates a variety of cellular functions by activating downstream signaling kinases (Sato 2013).
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Isotype: IgG1
Handling
- Quantity: 100 µl
- Storage: -20ºC only
- Buffer: Phosphate buffered saline, 0.09% Sodium Azide, PEG, Sucrose
Applications
- Western Blotting (WB)
