MOUSE ANTI HUMAN C1q

Mouse anti human C1q antibody, clone 004-43.X (3R9/2), recognizes human complement component 1 q (C1q), a ~156 kDa secreted protein. C1q associates with proenzymes C1r and C1s to form the calcium-dependent C1 complex, the first component of the serum complement system. C1q is composed of six A-, six B-chains and six C-polypeptide chains. Each chain contains a collagen-like region located near the N-terminus and a C-terminal globular region. These regions bind the Fc region of IgM and IgG molecules, initiating the classical pathway of complement activation. C1q deficiency has been associated with lupus erythematosus and glomerulonephritis (Troedson et al. 2013).

• Clonality: Monoclonal
• Host: Mouse
• Reactivity: Human
• Isotype: IgG1

• Quantity: 0.1 ml
• Storage: +4ºC, -20ºC if preferred
• Buffer: Borate buffered saline, 0.09% Sodium Azide

• ELISA (ELISA)
• Flow Cytometry (FC)
• Immunofluorescence (IF)
• Immunohistochemistry (Frozen Sections) (IHC (Fr))
• Western Blotting (WB)