Product & ReviewsAntibodies

MOUSE ANTI HUMAN CD120a

Product Details

Cat. No.
MCA1340
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
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Bio-Rad

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Description

Mouse anti Human CD120a antibody, clone H398 recognizes an extracellular domain of the ~55 kDa human TNF receptor (p55, TNF-R1, CD120a). No binding occurs to the ~75 kDa TNF receptor (CD120b). CD120a is weakly expressed by monocytes and granulocytes.Mouse anti Human CD120a antibody, clone H398 may be used to detect high levels of TNFR1, in western blotting under reducing conditions, such as recombinant material, but it is not suitable for detection of TNFR1 in normal cells in this application.Mouse anti Human CD120a antibody, clone H398 inhibits the biological activity of both natural and recombinant human TNFalpha and TNFbeta (Thoma et al. 1990 and Dri et al. 1999).Mouse anti Human CD120a antibody, clone H398 is routinely tested in flow cytometry on human peripheral blood monocytes.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human, Rabbit (Lapine)
  • Isotype: IgG2a

Handling

  • Quantity: 0.2 mg
  • Storage: +4ºC, -20ºC if preferred
  • Buffer: Phosphate buffered saline, 0.09% Sodium Azide

Applications

  • ELISA (ELISA)
  • Flow Cytometry (FC)
  • Radioimmunoassay (RIA)
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