Product & ReviewsAntibodies

MOUSE ANTI HUMAN CD178

Product Details

Cat. No.
MCA2408GA
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
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Bio-Rad

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Description

Mouse anti Human CD178 antibody, clone 10F2 recognizes the human CD178 cell surface antigen, a ~40 kDa glycoprotein also known as Fas ligand (CD95L).CD178 is a member of the TNF family, which is expressed by activated T lymphocytes and NK cells. The protein may exist as either a membrane bound or a cleaved soluble form. CD178 plays an important role in T cell development and cytotoxicity. Binding of CD178 to Fas (CD95) results in the induction of apoptosis. Mouse anti Human CD178 antibody, clone 10F2 is reported to block the activity of Fas ligand (Legembre et al. 2002).

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Isotype: IgG1

Handling

  • Quantity: 0.1 mg
  • Storage: +4ºC, -20ºC if preferred
  • Buffer: Phosphate buffered saline, 0.09% Sodium Azide

Applications

  • ELISA (ELISA)
  • Flow Cytometry (FC)
  • Immunoprecipitation (IP)
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