MOUSE ANTI HUMAN CD244

Mouse anti Human CD244 antibody, clone 2B4.69 recognizes the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4). CD244 is a 370 amino acid single pass type I transmembrane glycoprotein with two Ig-like V type domains. CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells.CD244 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of CD244 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.

• Clonality: Monoclonal
• Host: Mouse
• Reactivity: Human
• Isotype: IgG1

• Quantity: 0.2 mg
• Storage: +4ºC, -20ºC if preferred
• Buffer: Phosphate buffered saline, 0.09% Sodium Azide

• Flow Cytometry (FC)
• Immunoprecipitation (IP)