Product & ReviewsAntibodies

MOUSE ANTI HUMAN CD282

Product Details

Cat. No.
MCA2484
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
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Bio-Rad

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Description

Mouse anti Human CD282 antibody, clone 11G7 recognizes the human Toll-like receptor 2 (TLR2), a ~90 kDa type 1 transmembrane protein that is primarily expressed by peripheral blood monocytes. TLR2, also known as CD282, is reported to respond to a diverse range of bacterial cell wall components, mediating the innate immune response in co-operation with MD-2.Mouse anti Human CD282 antibody, clone 11G7 has been reported to block IL-6 cytokine production in response to ara-lipoarabinomannan (araLAM) and tripalmitoyl cysteinyl lipopeptide (Pam3CSK4) (Sandor et al. 2003). Clone 11G7 does not inhibit the production of cytokines induced by zymosan stimulation.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Isotype: IgG1

Handling

  • Quantity: 0.2 mg
  • Storage: +4ºC, -20ºC if preferred
  • Buffer: Phosphate buffered saline, 0.09% Sodium Azide

Applications

  • Flow Cytometry (FC)
  • Immunoprecipitation (IP)
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