MOUSE ANTI HUMAN CD289
Product Details
- Cat. No.
- MCA2265
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
Mouse anti Human CD289 antibody used for the evaluation of TLR9 expression
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Description
Mouse anti Human CD289 antibody, clone 5G5 recognizes human, canine and murine TLR9, otherwise known as CD289. TLR9 is a member of the Toll-like receptor (TLR) family and functions as a receptor for bacterial DNA (CpG-DNA), playing a fundamental role in pathogen recognition and activation of innate immunity.TLRs are expressed on the cell surface and the endocytic compartment and recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents.They also initiate cell signalling to induce production of cytokines necessary for the innate immunity and subsequent adaptive immunity. In mouse RAW264 cells TLR9 has been shown to be expressed intracellularly, but not at the cell surface.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Dog (Canine), Human, Mouse
- Isotype: IgG2a
Handling
- Quantity: 0.25 mg
- Storage: +4ºC, -20ºC if preferred
- Buffer: Phosphate buffered saline, 0.09% Sodium Azide, 1% BSA
Applications
- Flow Cytometry (FC)
- Immunohistochemistry (Frozen Sections) (IHC (Fr))
- Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
- Western Blotting (WB)
