MOUSE ANTI HUMAN CD36
Product Details
- Cat. No.
- MCA722
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
Figure A. Mouse anti Human CD14. Figure B. Mouse anti Human CD14 and Mouse anti Human CD36.
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Description
Mouse anti Human CD36 antibody, clone SMØ recognizes the CD36 antigen, an ~88 kDa cell surface glycoprotein expressed by platelets, monocytes/macrophages and also by some microvascular endothelium and erythroid precursors.CD36 is the receptor for thrombospondin. When expressed by monocytes and macrophages, CD36 acts as a receptor for oxidized LDL and for apoptotic polymorphonuclear cells. Mouse anti Human CD36 antibody, clone SMØ partially inhibits collagen induced platelet aggregation and macrophage ingestion of apoptotic human neutrophils. It has been reported that this antibody may activate platelets as measured by fibrinogen binding, P-Selectin expression and Annexin V binding - for further details please contact our Technical Services team.Mouse anti Human CD36 antibody, clone SMØ is also reported to block interaction of oxidised low-density lipoprotein (OXLDL) with CD36 (Sugihara et al.1992).
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Isotype: IgM
Handling
- Quantity: 0.2 mg
- Storage: +4ºC DO NOT FREEZE
- Buffer: Phosphate buffered saline, 0.09% Sodium Azide
Applications
- Flow Cytometry (FC)
- Immunohistochemistry (Frozen Sections) (IHC (Fr))
