Product & ReviewsAntibodies

MOUSE ANTI HUMAN CD54

Product Details

Cat. No.
MCA1615
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Bio-Rad

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Description

Mouse anti Human CD54 antibody, clone 15.2 recognizes the human CD54 cell surface antigen also known as intracellular Adhesion Molecule -1 (ICAM-1) or Major group rhinovirus receptor.CD54 is expressed by many cells following activation by inflammatory mediators. It is a 505 amino acid with an additional 27 amino acid signal peptide ~90 kDa single pass type I transmembrane glycoprotein bearing 5 Ig-like C2-type domains.Mouse anti Human CD54 antibody, clone 15.2 blocks CD54 function (Berendt et al. 1992). Mouse anti Human CD54 antibody, clone 15.2 binds to an epitope on the N-terminal Ig-like domain within a region designated the L43 loop (Chakravorty and Craig 2005).

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human, Pig (Swine)
  • Isotype: IgG1

Handling

  • Quantity: 0.2 mg
  • Storage: +4ºC, -20ºC if preferred
  • Buffer: Phosphate buffered saline, 0.09% Sodium Azide

Applications

  • Flow Cytometry (FC)
  • Immunohistochemistry (Frozen Sections) (IHC (Fr))
  • Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
  • Immunoprecipitation (IP)
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