Product & ReviewsAntibodies

MOUSE ANTI HUMAN CD56

Product Details

Cat. No.
MCA2693
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
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Bio-Rad

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Description

Mouse anti Human CD56 antibody, clone 123C3 recognizes human neural cell adhesion molecule (NCAM), otherwise known as CD56. The CD56 molecule is a cell surface glycoprotein which is expressed on neuroendocrine cells, natural killer cells and a subset of T cells in the peripheral blood. Three main isoforms of CD56 exist. Neurons express the largest 180 kDa form, while hemopoietic cells express the 140 kDa isoform. Mouse anti Human CD56 antibody, clone 123C3 recognizes both the 140 kDa and the 180 kDa isoform of the CD56 protein. In neuronal tissues, CD56 mediates homophilic and heterophilic adhesion and is implicated in neural development. Studies suggest that CD56 is also expressed on thyroid follicular epithelium and may play a role in autoimmune disease of the thyroid. CD56 is expressed in a range of tumours including tumours of the lung, neural derived malignancies and natural killer cell lymphomas.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Isotype: IgG1

Handling

  • Quantity: 0.2 mg
  • Storage: +4ºC, -20ºC if preferred
  • Buffer: Phosphate buffered saline, 0.09% Sodium Azide

Applications

  • ELISA (ELISA)
  • Flow Cytometry (FC)
  • Immunohistochemistry (Frozen Sections) (IHC (Fr))
  • Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
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