MOUSE ANTI HUMAN CD95
Product Details
- Cat. No.
- MCA1539
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
Figure A. Mouse anti Human CD45. Figure B. Mouse anti Human CD45 and Mouse anti Human CD95
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Description
Mouse anti Human CD95 antibody, clone LOB 3/17 recognizes the human CD95 cell surface antigen, also known as Tumor necrosis factor receptor superfamily member 6, Fas, Apo-1 antigen, Apoptosis-mediating surface antigen FAS or FASLG receptor. CD95 is a 310 amino acid ~40-50 kDa single pass type I transmembrane glycoprotein expressed by activated T and B cells, NK cells and thymocytes. Mutations in the CD95 gene, FAS can lead to the development of Autoimmune lymphoproliferative syndrome 1A (ALPS1A), an apoptotic disorder with early onset resulting in an accumulation of autoreactive lymphocytes (Peters et al. 1999).
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Rhesus Monkey
- Isotype: IgG1
Handling
- Quantity: 0.2 mg
- Storage: +4ºC, -20ºC if preferred
- Buffer: TRIS buffered saline, 0.09% Sodium Azide
Applications
- Flow Cytometry (FC)
- Immunoprecipitation (IP)
