MOUSE ANTI HUMAN CD96

Mouse anti Human CD96 antibody, clone NK92.39 recognizes human CD96, otherwise known as Tactile (T cell-activated increased late expression), a type I transmembrane glycoprotein expressed at low levels on peripheral resting T and NK cells, which increases following activation. CD96 stimulates the cytotoxicity of activated NK cells, and promotes the adhesion of NK cells to target cells expressing CD155/poliovirus receptor (PVR) and the transfer of target cell PVR to the NK cells. CD96 can be used in the immunophenotyping of T-cell acute lymphoblastic leukaemias (ALL) and acute myeloid leukaemias (AML), and may play a role in the recognition of CD155-expressing tumours by NK cells. Mouse anti Human CD96 antibody, clone NK92.39 blocks the binding of soluble CD155 to NK92 cells (Fuchs et al. 2004).

• Clonality: Monoclonal
• Host: Mouse
• Reactivity: Human
• Isotype: IgG1

• Quantity: 0.2 mg
• Storage: +4ºC, -20ºC if preferred
• Buffer: Phosphate buffered saline, 0.09% Sodium Azide

• Flow Cytometry (FC)