Product & ReviewsAntibodies

MOUSE ANTI HUMAN IgG4

Product Details

Cat. No.
MCA2098G
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
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Bio-Rad

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Description

Mouse anti Human IgG4 antibody, clone HP6025 recognizes the heavy chain of human IgG4, at an epitope in the Fc region. No cross-reactivity is observed with IgG1, IgG2, IgG3, IgM, IgA (Jefferis et al. 1985).Elevated levels of IgG4 and of IgG4 presenting plasma cells are frequently seen in patients with autoimmune pancreatitis (IAP) and inflammatory bowel disease (Navaneethan et al. 2011) and it is suggested that IAP may develop as a paraneoplastic syndrome in some cancer patients (Shiokawa et al. 2013)

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Chimpanzee, Human
  • Isotype: IgG1

Handling

  • Quantity: 0.2 mg
  • Storage: +4ºC, -20ºC if preferred
  • Buffer: Phosphate buffered saline, 0.09% Sodium Azide

Applications

  • ELISA (ELISA)
  • Immunoblotting (IB)
  • Immunohistochemistry (Frozen Sections) (IHC (Fr))
  • Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
  • Western Blotting (WB)
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