MOUSE ANTI HUMAN PROTEIN GENE PRODUCT 9.5
Product Details
- Cat. No.
- MCA4750GA
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
Immunostaining of rat spinal cord section with anti-mouse PGP9.5 and anti-neurofiliament H
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Description
Mouse anti Human protein gene product 9.5 monoclonal antibody, clone BH7 recognizes protein gene product 9.5 (PGP9.5) also known as ubiquitin C terminal hydrolase 1 (UCH-L1). UCH-L1 is a thiol protease that recognises and hydrolyses a peptide bond at the C-terminal glycine of ubiquitin. This protein is closely related to UCH-L3 and both are thought to recycle ubiquitin to maintain pools of monomeric ubiquitin necessary for proteolysis. UCH-L1 is expressed in neurons and cells of the diffuse neuroendocrine system and their tumours.UCH-L1 and UCH-L3 have been shown to have separate and overlapping functions in the maintanence of neurons of the gracile tract, nucleus tractus solitarius (NTS) and area postrema (Kurihara et al. 2001) .
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Bovine, Human, Mammalian, Mouse, Rat
- Isotype: IgG1
Handling
- Quantity: 0.1 ml
- Storage: +4ºC, -20ºC if preferred
- Buffer: Phosphate buffered saline, 0.065% Sodium Azide
Applications
- Immunofluorescence (IF)
- Western Blotting (WB)
