Product & ReviewsAntibodies

MOUSE ANTI HUMAN PROTEIN GENE PRODUCT 9.5

Product Details

Cat. No.
MCA4750GA
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Bio-Rad

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Description

Mouse anti Human protein gene product 9.5 monoclonal antibody, clone BH7 recognizes protein gene product 9.5 (PGP9.5) also known as ubiquitin C terminal hydrolase 1 (UCH-L1). UCH-L1 is a thiol protease that recognises and hydrolyses a peptide bond at the C-terminal glycine of ubiquitin. This protein is closely related to UCH-L3 and both are thought to recycle ubiquitin to maintain pools of monomeric ubiquitin necessary for proteolysis. UCH-L1 is expressed in neurons and cells of the diffuse neuroendocrine system and their tumours.UCH-L1 and UCH-L3 have been shown to have separate and overlapping functions in the maintanence of neurons of the gracile tract, nucleus tractus solitarius (NTS) and area postrema (Kurihara et al. 2001) .

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Bovine, Human, Mammalian, Mouse, Rat
  • Isotype: IgG1

Handling

  • Quantity: 0.1 ml
  • Storage: +4ºC, -20ºC if preferred
  • Buffer: Phosphate buffered saline, 0.065% Sodium Azide

Applications

  • Immunofluorescence (IF)
  • Western Blotting (WB)
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