MOUSE ANTI PIG CD117
Product Details
- Cat. No.
- MCA2598GA
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
Porcine Lymphocytes stained with Mouse anti Porcine CD117: Alexa Fluor® 488 (MCA2598A488)
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Description
Mouse anti Pig CD117, clone 2B8/BM is specific for porcine CD117, also known as c-kit, a 155 kDa type I transmembrane protein with protein tyrosine kinase activity, which plays an important role in early hematopoiesis (Perez et al. 2007). Hematopoietic stem cells (HSC) of bone marrow have multilineage differentiation potential and an extensive capacity for self-renewal. The majority of adult bone marrow hematopoietic progenitor cells are CD117+ and have been used successfully in xenograft transplantation models for long term survival of grafts, without symptoms of graft-versus-host disease (GVHD). Mouse anti pig CD117, clone 2B8/BM recognizes CD117 on a small subset of porcine bone marrow progenitor cells and therefore provides an alternative tool from the previously used c-kit ligand stem cell factor, for the isolation and enrichment of porcine stem cells.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Pig (Swine)
- Isotype: IgG1
Handling
- Quantity: 0.1 mg
- Storage: +4ºC, -20ºC if preferred
- Buffer: Phosphate buffered saline, 0.09% Sodium Azide
Applications
- Flow Cytometry (FC)
- Immunohistochemistry (Frozen Sections) (IHC (Fr))
- Immunoprecipitation (IP)
- Western Blotting (WB)
