Product & ReviewsAntibodies

MOUSE ANTI PIG CD4 ALPHA

Product Details

Cat. No.
MCA1749GA
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
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Bio-Rad

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Description

Mouse anti Porcine CD4 alpha, clone MIL17 recognizes a ~55 kDa porcine homologue to the human CD4 antigen found on the surface of helper-T cells. MIL-17 was confirmed as a member of the CD4 alpha cluster at the ‘Third International Workshop on Swine Leukocyte Differentiation Antigens’ (Haverson et al. 2001). Porcine CD4 is a type 1 trans-membrane member of the immunoglobulin superfamily.Pigs appear unusual amongst mammalian species as they appear to have four populations of resting T lymphocytes. In addition to the two populations of mutually exclusive CD4+/CD8- and CD4-/CD8+ lymphocytes, they also appear to have significant populations of CD4-/CD8- and CD4+/CD8+ cells. Lymphoblasts with a double positive phenotype have been described in other species but this is not the case for mature T lymphocytic calls (Saalmuller et al. 1987)Mouse anti Pig CD4 alpha, clone MIL17 stains a population of cells with characteristic lymphocyte morphology in immunohistochemistry (Inman et al. 2010).

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Pig (Swine)
  • Isotype: IgG2b

Handling

  • Quantity: 0.1 mg
  • Storage: +4ºC, -20ºC if preferred
  • Buffer: Phosphate buffered saline, 0.09% Sodium Azide

Applications

  • Flow Cytometry (FC)
  • Immunohistochemistry (Frozen Sections) (IHC (Fr))
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