Product & ReviewsAntibodies

MOUSE ANTI RAT CD161

Product Details

Cat. No.
MCA1427
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
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Bio-Rad

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Description

Mouse anti Rat CD161 antibody, clone 10/78 recognizes the rat Killer cell lectin-like receptor subfamily B protein, also known as NKR-PI or CD161. CD161 is a 233 amino acid ~60 kDa type II single pass protein containing a single C-type lectin domain. CD161 is expressed on rat NK cells and T cell subpopulations. CD161 exists in 2 forms NKR-PIa and NKR-PIb, Mouse anti Rat CD161 antibody, clone 10/78  recognizes both forms of CD161 (Li et al. 2003). Clone 10/78 competes with another anti CD161 clone, 3.2.3 for binding to antigen.Mouse anti Rat CD161 antibody, clone 10/78 has been successfully employed for the in vivo depletion of rat NK cells in an experimental obesity model (Wrann et al. 2010).

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Rat
  • Isotype: IgG1

Handling

  • Quantity: 0.25 mg
  • Storage: +4ºC, -20ºC if preferred
  • Buffer: Phosphate buffered saline, 0.09% Sodium Azide

Applications

  • Flow Cytometry (FC)
  • Immunohistochemistry (Frozen Sections) (IHC (Fr))
  • Immunoprecipitation (IP)
  • Radioimmunoassay (RIA)
  • Western Blotting (WB)
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