MOUSE ANTI SHEEP MHC CLASS II DQ DR POLYMORPHIC:RPE

Mouse anti Sheep MHC Class II DQ DR antibody, clone 28.1 recognizes a polymorphic epitope on ovine MHC class II DQ and DR molecules, which are constitutively expressed on antigen presenting cells such as dendritic cells, B lymphocytes, monocytes, macrophages, activated T lymphocytes and may be induced on a range of other cell types by interferon gamma.The major histocompatibility complex (MHC) is a cluster of genes some of which are important in the immune response to infections. In sheep, this complex is referred to as the ovine leukocyte antigen (OLA) region. There are 2 major types of MHC class IIa molecules encoded by the OLA which are DR and DQ each composed of an alpha and beta chain. Mouse anti Sheep MHC Class II DQ DR antibody, clone 28.1 recognizes ovine MHC II transfectants DQ - T28.1, DQ - T26.2 and DR - T31.3 but not DR - T8.1. (Ballingall, K. et al. 1995).

• Clonality: Monoclonal
• Host: Mouse
• Reactivity: Bovine, Goat, Sheep (Ovine)
• Isotype: IgG1

• Quantity: 100 TESTS
• Storage: +4ºC DO NOT FREEZE
• Buffer: Phosphate buffered saline, 0.09% Sodium Azide, 1% BSA, 5% Sucrose

• Flow Cytometry (FC)