MOUSE ANTI SYNAPTOPHYSIN

Mouse anti Human synaptophysin antibody, clone SY38 recognizes synaptophysin, also known as Major synaptic vesicle protein p38. Synaptophysin is a 313 amino acid ~38kDa multi pass transmembrane glycoprotein containing a single MARVEL domain. Synaptophysin is characteristic of small neurosecretory vesicles and is also present in neuroendocrine cells of neuronal and epithelial phenotype (UniProt: P08247). Synaptophysin is widely used as a marker for nerve terminals and for differentiating neuroendocrine tumours.Mouse anti Human synaptophysin antibody, clone SY38 has been used to detect synaptophysin in a number of neuronal and adrenal tumours including, pheochromocytomas, ganglioneuromas (Pace et al. 2002), neuroendocrine tumours of epithelial origin; pancreatic islet cell carcinoma, bronchial and gastrointestinal carcinoids and medullary carcinoma of the thyroid (Wiedenmann et al. 1986).

• Clonality: Monoclonal
• Host: Mouse
• Reactivity: Bovine, Human, Kangaroo, Mouse, Rat
• Isotype: IgG1

• Quantity: 25 µg
• Storage: +4ºC, -20ºC if preferred
• Buffer: Phosphate buffered saline, 0.09% Sodium Azide, 0.5% BSA

• Immunohistochemistry (Frozen Sections) (IHC (Fr))
• Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
• Western Blotting (WB)