Product & ReviewsAntibodies

MOZ rabbit antibody (pAb)

Product Details

Cat. No.
39867
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Active Motif

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Description

MOZ (Monocytic leukemia zinc finger protein) / MYST3 (also known KAT6A) is a histone acetyltransferase specific for H3. It is part of the MOZ/MORF protein complex and is involved in the activation of transcription. Specifically, it is known to interact with and serve as a co-activator for RUNX1 and RUNX2. MOZ / MYST3 is found concentrated in sub-nuclear foci that are distinct from PML bodies. Chromosomal aberrations involving MYST3 may be a cause of acute myeloid leukemias. MYST3-NCoA2 has been shown to bind CBP and disrupt its transcriptional activation function.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human
  • Isotype: IgG

Handling

  • Quantity: 100 ul
  • Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Applications

  • Western Blotting (WB)
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