Product & ReviewsAntibodies
MOZ rabbit antibody (pAb)
Product Details
- Cat. No.
- 39867
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
MOZ (Monocytic leukemia zinc finger protein) / MYST3 (also known KAT6A) is a histone acetyltransferase specific for H3. It is part of the MOZ/MORF protein complex and is involved in the activation of transcription. Specifically, it is known to interact with and serve as a co-activator for RUNX1 and RUNX2. MOZ / MYST3 is found concentrated in sub-nuclear foci that are distinct from PML bodies. Chromosomal aberrations involving MYST3 may be a cause of acute myeloid leukemias. MYST3-NCoA2 has been shown to bind CBP and disrupt its transcriptional activation function.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Isotype: IgG
Handling
- Quantity: 100 ul
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Western Blotting (WB)