Product & ReviewsAntibodies
MRP2 Antibody
Product Details
- Cat. No.
- 251463
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
MRP2 (Canalicular multispecific organic anion transporter 1) mediates hepatobiliary excretion of numerous organic anions. MRP2 is found on the apical membrane of polarized cells in the liver, kidney, intestine, with the highest expression in liver. Defects in MRP2 are the cause of Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia, an increase in the urinary excretion of coproporphyrin isomer I, deposition of melanin-like pigment in hepatocytes, and prolonged retention of sulfobromophthalein, but otherwise normal liver function.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human MRP2.
- Isotype: Rabbit Ig
- Gene: Q92887
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)