Product & ReviewsAntibodies
MSH2 Antibody
Product Details
- Cat. No.
- 200166
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
DNA mismatch repair protein Msh2 (MSH2) is a component of the post-replicative DNA mismatch repair system (MMR). MSH2 forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) that bind to DNA mismatches and initiate DNA repair. Defects in MSH2 are the cause of hereditary non-polyposis colorectal cancer type 1 and endometrial cancers.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Monkey, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human MSH2.
- Isotype: Rabbit Ig
- Gene: P43246, NP_000242
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)