Product & ReviewsAntibodies
MSH3 Rabbit pAb
Product Details
- Cat. No.
- A5681
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - MSH3 antibody (A5681)
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Description
The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
