Product & ReviewsAntibodies
MSH6 (3A10) Antibody
Product Details
- Cat. No.
- 252761
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
"MSH6 (DNA mismatch repair protein Msh6) mutations are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair. "
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: "Purified recombinant fragment of MSH6 expressed in E. coli. <br>"
- Clone: 3A10H7
- Isotype: Mouse IgG1
- Gene: P52701
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Western Blotting (WB)