Product & ReviewsAntibodies
Munc-18 (Ser515) Antibody
Product Details
- Cat. No.
- 252559
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Syntaxin-binding protein 2 (Munc-18) is involved in intracellular vesicle trafficking and vesicle fusion with membranes. Munc-18 contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Munc-18 regulates cytotoxic granule exocytosis in natural killer (NK) cells. The function of Munc-18 is regulated by PKC phosphorylation of Ser515.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Chicken, Dog (Canine), Human, Monkey, Mouse, Rat, Xenopus
- Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser515 of rat munc-18.
- Isotype: Rabbit Ig
- Modifications: Phosphospecific Antibody
- Gene: Q62753
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)