Product & ReviewsAntibodies
NANOG (1E6C) Antibody
Product Details
- Cat. No.
- 252838
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Nanog (Homeobox protein NANOG) is a transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Nanog imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Nanog blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: "Purified recombinant fragment of NANOG (aa20-166) expressed in E. coli. <br>"
- Clone: 1E6C4
- Isotype: Mouse IgG1
- Gene: Q80Z64
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunofluorescence (IF)
- Western Blotting (WB)