Product & ReviewsAntibodies
NEDD4 Rabbit mAb
Product Details
- Cat. No.
- A4385
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rabbit
Western blot - NEDD4 Rabbit mAb (A4385)
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Description
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016]
Biological Information
- Clonality: Monoclonal
- Host: Rabbit
- Reactivity: Human
