Product & ReviewsAntibodies

NF-M Antibody

Product Details

Cat. No.
253180
Type
Primary Antibody
Clonality
Polyclonal
Host
Chicken
Abbiotec

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Description

Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease.

Biological Information

  • Clonality: Polyclonal
  • Host: Chicken
  • Reactivity: Chicken, Human, Mouse, Rat
  • Antigen: Recombinant fusion protein containing the C-term region of rat NF-M expressed in E. coli.
  • Isotype: Chicken Ig
  • Gene: P12839

Handling

  • Quantity: 0.1 ml
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunofluorescence (IF)
  • Western Blotting (WB)
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