NF-M Antibody
Product Details
- Cat. No.
- 253180
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Chicken
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Description
Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease.
Biological Information
- Clonality: Polyclonal
- Host: Chicken
- Reactivity: Chicken, Human, Mouse, Rat
- Antigen: Recombinant fusion protein containing the C-term region of rat NF-M expressed in E. coli.
- Isotype: Chicken Ig
- Gene: P12839
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunofluorescence (IF)
- Western Blotting (WB)