Product & ReviewsAntibodies
NFkB p100 rabbit antibody (pAb)
Product Details
- Cat. No.
- 39687
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RelA/p65, RelB, NFkB1/p105, NFkB1/p50, Rel and NFkB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. The C-terminus of p100 might be involved in cytoplasmic retention, inhibition of DNA-binding by p52 homodimers, and/or transcription activation.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Isotype: IgG
Handling
- Quantity: 100 ul
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Western Blotting (WB)