Product & ReviewsAntibodies
NGF-beta Antibody
Product Details
- Cat. No.
- 250773
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Nerve growth factor (NGF) is important for the development , differentation, and survival of a variety of neuronal and non-neuronal cells. NGF action is mediated by binding to two distinct receptors, the high affinity p140 and low affinity p75 NGF receptors. P75NGFR binds neurotrophins including brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), neurotrophin 4/5 (NT-4/5) and NT-6. p75NGFR belongs to the TNF-R superfamily reported to mediate NGF-induced apoptosis. Defects in NGF are the cause of hereditary sensory and autonomic neuropathies.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NGF.
- Isotype: Rabbit Ig
- Gene: P01138
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)