Product & ReviewsAntibodies
NGFR (2F1C) Antibody
Product Details
- Cat. No.
- 252943
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
NGFR (p75NTR) is a low affinity neurotrophin receptor. NGFR binds neurotrophins including NGF, brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and NT-4. Nerve growth factor (NGF) is important for the development, differentation, survival of a variety of neuronal and non-neuronal cells. NGF action is mediated by binding to two distinct receptors, the high affinity p140 and low affinity p75 NTR (NGFR). NGFR is a TNF-R superfamily member, reported to mediate NGF-induced apoptosis.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of human NGFR expressed in E. coli.
- Clone: 2F1C2
- Isotype: Mouse IgG1
- Gene: P08138
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Flow Cytometry (FC)
- Immunofluorescence (IF)
- Western Blotting (WB)