Product & ReviewsAntibodies
NMDAR2B (Tyr1252) Antibody
Product Details
- Cat. No.
- 252561
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Glutamate [NMDA] receptor subunit epsilon-2 (N-methyl D-aspartate receptor subtype 2B receptor or NMDA NR2B) is a NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. NMDA NR2B forms heteromeric channel of a zeta subunit, a epsilon subunit (GRIN2A , GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). NMDA NR2B is sprimarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells. Phosphorylation of Tyr1252 is thought to potentiate NMDA receptor-dependent influx of calcium.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Chicken, Dog (Canine), Human, Mouse, Zebrafish
- Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Tyr1252 of rat NMDA NR2B.
- Isotype: Rabbit Ig
- Modifications: Phosphospecific Antibody
- Gene: Q00960
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)