Product & ReviewsAntibodies

NMDAR2B (Tyr1336) Antibody

Product Details

Cat. No.
252562
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Abbiotec

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Description

Glutamate [NMDA] receptor subunit epsilon-2 (N-methyl D-aspartate receptor subtype 2B receptor or NMDA NR2B) is a NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. NMDA NR2B forms heteromeric channel of a zeta subunit, a epsilon subunit (GRIN2A , GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). NMDA NR2B is sprimarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells. Phosphorylation of Tyr1336 is thought to potentiate NMDA receptor-dependent influx of calcium and ischemia may also increase the phosphorylation of this site.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human, Monkey, Mouse, Rat
  • Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Try1336 of rat NMDA NR2B.
  • Isotype: Rabbit Ig
  • Modifications: Phosphospecific Antibody
  • Gene: Q00960

Handling

  • Quantity: 0.1 ml
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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