NME1 Rabbit pAb
Product Details
- Cat. No.
- A0259
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - NME1 antibody (A0259)
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Description
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
Handling
- Specificity: 3
Applications
Performs well also at the low endogenous level of expression.
Western blot
I used the anti NME1 antibody (A0259) diluted in 1x PBS at a concentration of 1: 500 in metastatic cell lines showing low levels of NME1. The quality and sensitivity are very good however the antibody also recognizes the NME2 isoform.
Review Date: 21 Jun 2021 | ABclonal Technology
