Product & ReviewsAntibodies
NTP Antibody
Product Details
- Cat. No.
- 250794
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Neuronal thread protein (NTP) is composed almost entirely of Alu repeat sequences, and the mRNA encoding this protein is expressed in neurons. Overexpression of NTP is associated with neurofibrillary tangles of Alzheimer's disease. Both CSF and urine levels of NTP have been investigated as a biochemical marker of Alzheimer's disease. In vitro studies have also demonstrated that abnormal expression of this protein promotes neuritic sprouting and cell death, which is associated with dementia in Alzheimer's disease.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human NTP.
- Isotype: Rabbit Ig
- Gene: AF010144
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)