Product & ReviewsAntibodies
Nucleophosmin Antibody
Product Details
- Cat. No.
- 252120
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Nucleophosmin is involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors TP53/p53 and ARF. Nucleophosmin binds ribosomes presumably to drive ribosome nuclear export. Nucleophosmin associates with nucleolar ribonucleoprotein structures and binds single-stranded nucleic acids. Nucleophosmin acts as a chaperonin for the core histones H3, H2B and H4. A chromosomal aberration in nucleophosmin is found in a form of non-Hodgkin lymphoma.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human nucleophosmin.
- Isotype: Rabbit Ig
- Gene: P06748
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)