Product & ReviewsAntibodies
Nurr1 Antibody
Product Details
- Cat. No.
- 250795
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Nuclear receptors and transcription factors play a role in the development and maintenance of neurons that synthesize the neurotransmitter dopamine. The NURR1 gene encodes a 67-kDa member of the steroid-thyroid hormone-retinoid receptor superfamily. The orphan nuclear receptor NURR1 may function as a general coactivator of gene transcription and transcription factor. Mutations in Nurr1 have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophrenia, and maniac depression. Misregulation of Nurr1 may be associated with rheumatoid arthritis.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NURR1.
- Isotype: Rabbit Ig
- Gene: P43354
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)